Cardiovascular malformations in infants of diabetic mothers

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CONGENITAL HEART DISEASE Cardiovascular malformations in infants of diabetic mothers

Objective: To compare the prevalence at live birth and the spectrum of cardiovascular malformations in infants born to diabetic mothers with pre-existing diabetes with that in infants of non-diabetic mothers. Design: Prospective study of all live births in the resident population of one health region, with recording of details of the outcome of all pregnancies of women with pre-existing diabete...

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Congenital malformations in infants of diabetic mothers.

DURING the last two decades the outcome of pregnancy in the diabetic has improved greatly. In the Royal Maternity Hospital, Belfast, for example, the total fetal loss and perinatal mortality during the years 1972-78 have been 4.3 and 3.2 per cent respectively, whereas in earlier years figures well in excess of 10 per cent were common everywhere. In view of this the contribution of congenital ma...

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cardiovascular malformations in infants of diabetic mothers: a retrospective case-control study

maternal diabetes has teratogenic effects on the evolution of the fetal cardiovascular system; as a consequence, cardiovascular malformations are the most common anomalies in infants of diabetic mothers. the present study focuses on the association of all types of diabetes in mothers with the incidence of congenital cardiovascular malformations in their infants. in this retrospective case-contr...

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Infants of diabetic mothers.

9 Grodsky, G. M., and Forsham, P. H.: An immunochemical assay of total extractable insulin in man. J. Clin. Invest. 39:1070, i960. 10 Field, J. B., and Woodson, M. L.: Studies on the circulating insulin inhibitor found in some diabetic patients exhibiting chronic insulin resistance. J. Clin. Invest. 38:551, 1959. 11 Mitchell, M. L.: Interaction of radioinsulin with serum proteins in vitro and w...

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Infants of diabetic mothers.

Advances in the management of the mother with diabetes have reduced the rate of morbidity and mortality for her infant. Aggressive control of maternal glycemic status is warranted, because most morbidities are epidemiologically and pathophysiologically closely linked to fetal hyperglycemia and hyperinsulinemia. The burgeoning public health problem of overweight and obesity in children will like...

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ژورنال

عنوان ژورنال: Heart

سال: 2003

ISSN: 0007-0769

DOI: 10.1136/heart.89.10.1217